Methylmethacrylate and atrioventricular conduction in dogs.

The effect of intravenous methylmethacrylate (MMA) on atrioventricular conduction times was studied in dogs, utilizing His-bundle electrograms. Dogs were anesthetized with halothane or enflurane; then MMA in a dose causing minimal to profound hemodynamic changes was administered and His-bundle electrograms, and arterial, pulmonary artery, and central venous pressures were recorded. This experimental model did not demonstrate a prolongation of atrioventricular conduction intervals which could be implicated as etiologic in MMA-induced dysrhythmias.