通过血浆置换治疗急性感染后多发性神经病。

Treatment of acute post-infective polyneuropathy by means of plasma exchange.

作者信息

Bezwoda W R, Fritz V, Reef H E, Staub H, Derman D P, Lewis M, Kallenbach J, Zaltzman M, Naughton M A

出版信息

Acta Neurol Scand. 1984 Feb;69(2):112-9. doi: 10.1111/j.1600-0404.1984.tb07787.x.

DOI:10.1111/j.1600-0404.1984.tb07787.x

Abstract

15 patients with acute post-infective polyneuropathy of the Guillain-Barré type have been treated by means of plasma exchange. The clinical course and outcome of these patients is compared to that in a retrospectively matched control series who were treated with supportive therapy only. All patients had severe rapidly evolving muscle weakness and approximately half the patients in each group required ventilatory assistance. Both the duration of muscle weakness and the hospitalisation time was significantly shorter in the patients treated by means of plasma exchange. These results suggest that plasma exchange is of significant benefit in the treatment of patients with the Guillain-Barré syndrome.

摘要

15例吉兰-巴雷型急性感染后多发性神经病患者接受了血浆置换治疗。将这些患者的临床病程和结果与仅接受支持性治疗的回顾性匹配对照组进行比较。所有患者均有严重且迅速进展的肌无力，每组约一半患者需要通气支持。接受血浆置换治疗的患者肌无力持续时间和住院时间均明显缩短。这些结果表明，血浆置换对吉兰-巴雷综合征患者的治疗具有显著益处。