Clark M C, Flick M R
Am Rev Respir Dis. 1984 Apr;129(4):633-5.
A 22-yr-old man developed severe pulmonary edema after blowing air into tubing connected to a catheter inserted in a vein in his forearm. Pulmonary edema was rapid in onset, peaking in intensity about 12 h after the air had been insufflated. The patient's edema fluid to plasma protein concentration ratio of 0.79 showed that the edema fluid was rich in protein. Vascular pressures were normal except for mild pulmonary arterial hypertension and systemic hypotension. The patient's clinical course, edema fluid protein concentration, and vascular pressures were characteristic of an increased microvascular permeability type of pulmonary edema. The patient recovered fully within 48 h of the air infusion. His response to venous air embolism was similar to findings in an experimental model of pulmonary edema in sheep infused with venous air emboli. As long as air is not infused continuously for long periods or in very large amounts, this disorder is probably self-limiting, and supportive care may be the only treatment necessary.
一名22岁男性在向连接于前臂静脉插入导管的 tubing 吹气后发生严重肺水肿。肺水肿起病迅速，在注入空气后约12小时强度达到峰值。患者水肿液与血浆蛋白浓度之比为0.79，表明水肿液富含蛋白质。除轻度肺动脉高压和全身性低血压外，血管压力正常。患者的临床病程、水肿液蛋白浓度和血管压力具有微血管通透性增加型肺水肿的特征。患者在注入空气后48小时内完全康复。他对静脉空气栓塞的反应与注入静脉空气栓塞的绵羊肺水肿实验模型中的发现相似。只要空气不是长时间或大量持续注入，这种病症可能是自限性的，支持性护理可能是唯一必要的治疗方法。
