Goldstein W M, Barmada R
Arch Phys Med Rehabil. 1984 May;65(5):239-42.
The postoperative management of repaired medial collateral ligaments is controversial. There are proponents for either early mobilization or immobilization. To contribute to an understanding of the issues, 24 adult Dutch rabbits were divided into four groups and a comparative study was made of their incised medial collateral ligaments, contrasting early immobilization with mobilization at three and six weeks. The ligaments were studied histologically and biomechanically. At three weeks, the immobilized ligaments were twice as strong as mobilized ligaments. Histologically, the immobilized ligaments demonstrated more fibroblastic reaction while the mobilized ligaments showed more mature tissue development at the repair site. There were no statistically significant differences between knees mobilized for six weeks and knees immobilized for three weeks and then subsequently mobilized for three weeks. In view of these results, the authors conclude that the deleterious effects of immobilization should be considered when planning postoperative or postinjury treatment of torn medial collateral ligaments.
内侧副韧带修复术后的管理存在争议。对于早期活动或固定，均有支持者。为了有助于理解这些问题，将24只成年荷兰兔分为四组，对其切开的内侧副韧带进行了比较研究，对比了早期固定与在三周和六周时活动的情况。对韧带进行了组织学和生物力学研究。在三周时，固定的韧带强度是活动韧带的两倍。组织学上，固定的韧带显示出更多的成纤维细胞反应，而活动的韧带在修复部位显示出更成熟的组织发育。六周活动的膝关节与固定三周后再活动三周的膝关节之间没有统计学上的显著差异。鉴于这些结果，作者得出结论，在计划内侧副韧带撕裂的术后或伤后治疗时，应考虑固定的有害影响。
