Tanganelli P, Toti P, Weber E, Resi L, Chini B
Boll Soc Ital Biol Sper. 1984 Mar 30;60(3):549-51.
The presence of the diffuse intimal thickening (DIT) is commonly considered the structural basis for the early atherosclerotic involvement of the coronary arteries. In the ambit of a systematic morphometric comparison of experimental atherosclerotic plaques of aorta and coronaries, we have studied the coronary medio-intimal junctions of 4 months old rabbits. Both at sub-epicardic and intra-myocardic coronary arteries level we have found fiber structures similar to DIT. These findings may help explaining why coronary atherosclerosis in rabbits does not represent, in the usual experimental models, a lesion particularly severe nor of precocious appearance.
弥漫性内膜增厚（DIT）的存在通常被认为是冠状动脉早期动脉粥样硬化累及的结构基础。在对主动脉和冠状动脉的实验性动脉粥样硬化斑块进行系统形态计量学比较的范围内，我们研究了4个月大兔子的冠状动脉中膜-内膜交界处。在 epicardic下和心肌内冠状动脉水平，我们都发现了类似于DIT的纤维结构。这些发现可能有助于解释为什么在通常的实验模型中，兔子的冠状动脉粥样硬化并不表现为特别严重或早熟的病变。
