Markin V S, Kozlov M M
Biofizika. 1984 Jan-Feb;29(1):65-9.
A theory is developed which explains the temperature shift of phase transition of bilayer delta Tc resulting from the interaction of charged polar heads of lipid molecules. It has been shown that adsorption of monovalent cations on the strongly charged membrane increases the transition temperature by about 15 degrees, this value being independent of the ionic strength and dielectric permeability epsilon of the medium. When divalent cations are adsorbed the temperature shift of transition is larger, the value delta Tc depending on medium epsilon, where the polar heads are located. If the membrane is in the electrolyte solution delta Tc approximately equal to 19 degrees; when a dehydrated contact with low dielectric permeability is initiated between the membranes, the transition temperature in this zone is to increase by about 160 degrees, which well agrees with the experimental data.
提出了一种理论，该理论解释了由于脂质分子带电极性头部的相互作用而导致的双层相变温度偏移ΔTc。研究表明，单价阳离子在强带电膜上的吸附使转变温度升高约15度，该值与介质的离子强度和介电常数ε无关。当吸附二价阳离子时，转变的温度偏移更大，ΔTc值取决于极性头部所在介质的ε。如果膜处于电解质溶液中，ΔTc约等于19度；当膜之间开始与低介电常数的脱水接触时，该区域的转变温度将升高约160度，这与实验数据非常吻合。
