Takagi M
Exp Neurol. 1984 May;84(2):358-63. doi: 10.1016/0014-4886(84)90232-2.
The muscarinic versus nicotinic effects of acetylcholine (ACh) on the activity of cells in the interpeduncular nucleus (IPN) of guinea pig brain slices were investigated using electrophysiologic techniques. Nicotinic and muscarinic drugs acted postsynaptically to increase the firing rate of cells in the IPN. The excitatory actions of ACh were blocked both by atropine and by d-tubocurarine. These results indicated that cholinergic receptors of IPN cells seem to have both nicotinic and muscarinic characteristics.
利用电生理技术研究了乙酰胆碱（ACh）对豚鼠脑片脚间核（IPN）细胞活性的毒蕈碱样和烟碱样作用。烟碱样和毒蕈碱样药物通过突触后作用增加了IPN中细胞的放电频率。ACh的兴奋作用被阿托品和d -筒箭毒碱阻断。这些结果表明，IPN细胞的胆碱能受体似乎同时具有烟碱样和毒蕈碱样特性。
