Wolff M, Rosai J, Wright D H
Hum Pathol. 1984 Apr;15(4):341-3. doi: 10.1016/s0046-8177(84)80032-5.
Sebaceous glands in the thymus were discovered in three patients--two with myasthenia gravis and the other, who was operated on because of aortic valvular disease--with an unsuspected thymoma. Sebaceous glands not associated with hair follicles occur in diverse sites, the majority of which are in the head and neck or anogenital regions. Although most of these sites arise from the ectoderm, sebaceous glands have been reported in a thyroglossal duct, the larynx, and the esophagus, which are entodermal structures. Thus, precedents for ectodermally derived sebaceous glands in endodermal sites exist, but sebaceous glands have not previously been reported in the thymus. The authors speculate that their occurrence in the thymus may be related to the reported ectodermal contribution to the developing thymus by the epibranchial placode or cervical sinus.
在三名患者的胸腺中发现了皮脂腺——两名患有重症肌无力，另一名因主动脉瓣疾病接受手术——均伴有未被怀疑的胸腺瘤。不与毛囊相关的皮脂腺出现在不同部位，其中大多数位于头颈部或肛门生殖器区域。虽然这些部位大多起源于外胚层，但甲状腺舌管、喉和食管（均为内胚层结构）中也有皮脂腺的报道。因此，内胚层部位存在外胚层来源皮脂腺的先例，但此前胸腺中尚未有皮脂腺的报道。作者推测，它们在胸腺中的出现可能与报道的鳃上板或颈窦对外胚层对发育中胸腺的贡献有关。
