Negro P, Tuscano D, Flati D, Flati G, Carboni M
J Chir (Paris). 1984 Feb;121(2):133-9.
Operative risks of transduodenal sphincterotomy (T.D.S.) are the principal subject of discussion between those surgeons who practice the operation and those that condemn it. An international survey of 25, 541 cases treated by 130 surgeons showed that the incidence of specific complications such as acute pancreatitis (0.6 p. 100), hemorrhage (0,65 p. 100), and early cholangitis (0,5 p. 100), and relative mortality were lower than those usually reported by surgeons attributing an excessive operative risk to the procedure. Data was also obtained indicating that certain "risk factors" due to teh surgical technique were statistically significant (X2 test) and that knowledge of these enabled complications to be avoided. Morbidity and mortality of TDS could then be reduced to the level of those common to biliary tract surgery.
十二指肠括约肌切开术（T.D.S.）的手术风险是实施该手术的外科医生和谴责该手术的外科医生之间讨论的主要话题。一项对130名外科医生治疗的25541例病例的国际调查显示，诸如急性胰腺炎（0.6%）、出血（0.65%）和早期胆管炎（0.5%）等特定并发症的发生率以及相对死亡率低于那些认为该手术存在过高手术风险的外科医生通常报告的水平。还获得的数据表明，某些因手术技术导致的“风险因素”具有统计学意义（X²检验），了解这些因素能够避免并发症。然后，十二指肠括约肌切开术的发病率和死亡率可以降低到胆道手术常见的水平。
