Beeber A R, Kline M D, Pies R W, Manring J M
J Nerv Ment Dis. 1984 May;172(5):301-3. doi: 10.1097/00005053-198405000-00009.
There is considerable disagreement about the relationship between borderline personality disorder and the affective disorders. The authors report the results of a study of the relationship between dexamethasone suppression and depressive subtype in hospitalized depressed borderline patients. Twenty-three patients met research criteria for unipolar major depressive episode without psychosis of at least moderate severity. Thirteen patients also met criteria for borderline personality disorder. Dexamethasone suppression test (DST) results showed no significant correlation with either melancholia or borderline personality disorder alone. However, of the 13 borderlines, eight failed to suppress and six of those eight were not melancholic. The authors conclude that abnormal response to dexamethasone in nonmelancholic borderlines casts some doubt on the specificity of the DST for melancholia.
关于边缘型人格障碍与情感障碍之间的关系存在相当大的分歧。作者报告了一项关于住院的边缘型抑郁症患者地塞米松抑制与抑郁亚型之间关系的研究结果。23名患者符合至少中度严重程度的无精神病性症状的单相重度抑郁发作的研究标准。13名患者也符合边缘型人格障碍的标准。地塞米松抑制试验（DST）结果显示，单独与忧郁症或边缘型人格障碍均无显著相关性。然而，在这13名边缘型人格障碍患者中，有8名抑制功能未正常发挥，其中这8名中的6名并非忧郁症患者。作者得出结论，非忧郁症边缘型人格障碍患者对地塞米松的异常反应使人对DST针对忧郁症的特异性产生了一些怀疑。
