Marberger M, Altwein J E, Straub E, Wulff S H, Hohenfellner R
J Urol. 1978 Aug;120(2):216-9. doi: 10.1016/s0022-5347(17)57113-x.
The Lich-Gregoir antireflux procedure is a simple and safe method for the treatment of primary reflux of all grades if the ureter is not grossly dilated on the excretory urogram. Reflux was cured in 97.7 per cent of 429 ureters in 371 children. A stenosis of the terminal ureter requiring reimplantation occurred in 0.5 per cent. The over-all rate of reinterventions was 3.7 per cent. This low complication rate makes surgical correction of reflux advisable if urinary tract infection and primary reflux cannot be eradicated by continuous antimicrobial therapy within 6 months.
如果排泄性尿路造影显示输尿管没有明显扩张，利希-格雷瓜尔抗反流手术是一种治疗各级原发性反流的简单且安全的方法。371名儿童的429条输尿管中，97.7%的反流得到治愈。0.5%的病例出现输尿管末端狭窄，需要重新植入。再次干预的总体发生率为3.7%。如果6个月内持续抗菌治疗无法根除尿路感染和原发性反流，这种低并发症发生率使得手术纠正反流是可取的。
