Gierup H J, Hakelius L
J Urol. 1978 Aug;120(2):223-6. doi: 10.1016/s0022-5347(17)57117-7.
Urinary incontinence owing to epispadias or bladder exstrophy is a difficult therapeutic problem. To improve the results a new method, including free autogenous muscle transplantation, was developed. Before transplantation a skeletal muscle (extensor brevis of the foot) is denervated and, 2 weeks later, it is transplanted and placed as a U-sling around the urethra in close contact with normally innervated muscles, which act as reinnervation sources. Two patients showed improvement of continence and increasing bladder capacity from 6 weeks after transplantation. Postoperative cine-studies of micturition demonstrated clearly the functional properties of the transplanted muscle.
因尿道上裂或膀胱外翻导致的尿失禁是一个棘手的治疗难题。为了提高治疗效果,研发了一种新方法,包括自体游离肌肉移植。移植前,对一块骨骼肌(足短伸肌)进行去神经支配,两周后将其移植并环绕尿道呈U形吊带放置,使其与具有正常神经支配的肌肉紧密接触,这些肌肉作为神经再支配的来源。两名患者在移植后6周出现控尿改善且膀胱容量增加。术后排尿的电影造影研究清楚地显示了移植肌肉的功能特性。