Determination of halothane ED-50 in Mongolian gerbils (Meriones unguiculatus).
作者信息
Thielhart L M, Reitan J A, Martucci R W
出版信息
Lab Anim Sci. 1984 Feb;34(1):75-6.
PMID:6716962
Abstract
The effective dose-50 (ED-50) for halothane anesthesia was studied in 45 male Mongolian gerbils at age 12 weeks. Close control of circadian variation and animal temperature was maintained. Regression analysis for the percent of animals moving in response to a standard stimulus revealed an ED-50 of 1.32 volumes %, a concentration that approximates the ED-50 of the rat.
摘要
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