Goldin R, Brickman A S, Massry S G, Bluestone R
JAMA. 1978 Aug 25;240(8):759-61.
An attempt was made to determine whether a relationship exists between ankylosing spondylitis (AS) and hyperparathyroidism (HP). Twenty patients with definite AS, studied for biochemical evidence of HP, did not show consistent abnormalities in serum calcium, phosphorus, alkalinephosphatase, or parathyroid hormone levels or in bone-density measurements. Reviewing roentgenograms of 39 patients with HP showed one patient with sacroiliitis, and one of the 28 hyperparathyroid patients tissue-typed as HLA B27-positive. Both AS and HP are independent entities that have no causative or pathological relationship to each other.
本研究旨在确定强直性脊柱炎（AS）与甲状旁腺功能亢进症（HP）之间是否存在关联。对20例确诊为AS的患者进行了HP的生化证据研究，结果显示血清钙、磷、碱性磷酸酶、甲状旁腺激素水平或骨密度测量均未出现一致的异常。回顾39例HP患者的X线片，发现1例患者患有骶髂关节炎，28例甲状旁腺功能亢进患者中有1例组织分型为HLA B27阳性。AS和HP均为独立的疾病实体，彼此之间不存在因果关系或病理联系。
