Gentile S, Porcellini M, Saponara A, Stroffolini T, Loguercio C, Garofano M L, D'Ambrosi E, Coltorti M
Minerva Med. 1984 Mar 31;75(13):713-24.
This is the first of a series of reports on diabetic neuropathy. Peripheral or somatic diabetic neuropathy is discussed with reference to its major symptoms: central, peripheral and amyotrophic mononeuropathies, symmetrical and asymmetrical polyneuropathies, peripheral arthropathy and finally diabetic cachexia. The various theories on the pathogenesis of peripheral neuropathy are presented. Finally data on 173 type I and II diabetics are presented. These patients, treated in outpatients departments, were paired by sex, weight and age with an equal number of non-diabetic subjects. The results of the survey largely confirm report in the literature. The importance of continuous medical surveillance for the identification and hence prevention of diabetic neuropathy is emphasized. This is particularly necessary since we have still much to learn about the natural history of the disease and for the moment the therapeutic approaches to the various neuropathies concerned are both tentative and symptomatic.
这是关于糖尿病性神经病变系列报告的第一篇。本文将参照外周或躯体性糖尿病性神经病变的主要症状进行讨论:中枢性、外周性和肌萎缩性单神经病变,对称性和非对称性多发性神经病变,外周关节病,以及最后的糖尿病恶病质。文中还介绍了关于外周神经病变发病机制的各种理论。最后给出了173例I型和II型糖尿病患者的数据。这些在门诊接受治疗的患者,按照性别、体重和年龄与数量相等的非糖尿病受试者进行配对。调查结果在很大程度上证实了文献中的报道。强调了持续医学监测对于识别并因此预防糖尿病性神经病变的重要性。这一点尤为必要,因为我们对该疾病的自然史仍有很多需要了解的地方,而且目前针对各种相关神经病变的治疗方法都是试探性的且只是对症治疗。