Kaplan S L, Catlin F I, Weaver T, Feigin R D
Pediatrics. 1984 May;73(5):575-8.
Auditory brainstem responses were evaluated in 37 children with bacterial meningitis within 48 hours of admission. Four children (two with Haemophilus influenzae type b, and two with Streptococcus pneumoniae) had definite abnormalities of hearing detected at admission. Two of these children had severe-to-profound hearing losses which have persisted. Hearing losses were greatly reduced in the other two children (one child also was ataxic) when repeat testing was performed. Auditory brainstem responses in two additional children suggested brainstem dysfunction at admission (one child died and the other has had severe sequelae). Hearing losses occur early in the course of bacterial meningitis in some children. Further studies are required to confirm the use of auditory brainstem responses in detecting hearing losses early in high-risk children with bacterial meningitis.
在37名细菌性脑膜炎患儿入院48小时内对其听觉脑干反应进行了评估。4名儿童（2名b型流感嗜血杆菌感染，2名肺炎链球菌感染）在入院时被检测出存在明确的听力异常。其中2名儿童患有重度至极重度听力损失，且持续存在。另外2名儿童（其中1名儿童还伴有共济失调）在进行重复测试时听力损失大幅减轻。另有2名儿童的听觉脑干反应提示入院时存在脑干功能障碍（1名儿童死亡，另1名有严重后遗症）。部分儿童在细菌性脑膜炎病程早期会出现听力损失。需要进一步研究以证实听觉脑干反应在早期检测细菌性脑膜炎高危儿童听力损失中的应用价值。
