[Somatotropin-synthesizing activity of the in vitro cultured adenohypophyses of intact, hypo- and hyperthyroid rats].

Somatotropin-synthetizing activity of the adenohypophyses cultivated in vitro in eu-, hupo- and hyperthyroid rats was investigated. The most pronounced persistence of the activity (89%) within 12 days is seen in the adenohypophyses of hypothyroid rats and less evident (41%) in the adenohypophyses of hyperthyroid animals in comparison with that of euthyroid rats (66%). The activity rise in the adenohypophyses of euthyroid hypothyroid rats is observed by the 6th day of cultivation, being more pronounced in the adenohypophyses of hypo- than euthyroid animals. The adenohypophyses cultivated in vitro in hypo- and hyperthyroid rats may serve as models for studying the adenohypophyseal somatotropic function disorders in hypo- and hyperthyroses.