Le Magnen J, Devos M
Physiol Behav. 1984 Jan;32(1):39-44. doi: 10.1016/0031-9384(84)90067-2.
Meal to meal energy balance was examined in thirty-eight simultaneous recordings of feeding pattern and O2 consumption in six rats. The mean difference between energy intake in a meal and energy expenditure until the onset of the next meal was found positive at night and negative during day time. At night the excess of meal intake over meal to meal expenditures was decreasing from the beginning to the end of the night and was strongly correlated to meal sizes. During day time meal to meal deficit was decreasing from the beginning to the end of the period but was not correlated to meal sizes. These meal location and size effects on the meal to meal energy balance were not determined by an effect of these factors on metabolic rate. No indication was provided that meal to meal energy balance was influenced by a "meal induced thermogenesis." Rather an evolution from the beginning to the end of the night of the correlation between meal size and durations of meal to meal intervals was found to be parallel to the evolution of positive meal to meal energy balance throughout the night. From these data it is concluded that at night a dual utilization of meal caloric intake (current energy metabolism plus fat storage) and a dual source of fuel during the day (food plus mobilized fats) determine time and mechanism of meal onset.
在六只大鼠中同时记录进食模式和氧气消耗，共进行了38次实验，以此研究餐间能量平衡。结果发现，夜间一餐的能量摄入量与下一餐开始前的能量消耗之间的平均差异为正，而白天则为负。夜间，餐摄入量超过餐间支出的量从夜间开始到结束逐渐减少，且与餐量密切相关。在白天，餐间亏空从该时间段开始到结束逐渐减少，但与餐量无关。这些餐的位置和大小对餐间能量平衡的影响并非由这些因素对代谢率的影响所决定。没有迹象表明餐间能量平衡受到“食物诱导产热”的影响。相反，发现从夜间开始到结束，餐量与餐间间隔持续时间之间的相关性演变与整个夜间正的餐间能量平衡的演变是平行的。从这些数据可以得出结论，夜间对餐热量摄入的双重利用（当前能量代谢加脂肪储存）和白天燃料的双重来源（食物加动员的脂肪）决定了进餐开始的时间和机制。
