Strauss B, Gross J
Psychiatr Prax. 1984 Mar;11(2):49-55.
As a review of the literature concerning sexual side effects of psychotropic drugs in psychiatric patients reveals, sexual disturbances (such as erectile or orgasmic dysfunctions) seem to be a common consequence of psychopharmacological treatment. The frequency and relevance of these effects in psychiatric practice were estimated in a questionnaire study with 68 psychiatrists, working either in a practice or a clinic. According to the physicians answers, few patients report sexual side effects of drugs spontaneously, through these are supposed to be more common. Different kinds of sexual impairment are reported as specific effects of the drugs. As the physicians assume these effects generally provide a problem, both for the patients self-esteem as well as for treatment and compliance. Based on the psychiatrists experience patients are in a surprisingly good position to differentiate between the influences of their basic illness and a specific medication as far as sexual changes are concerned. One part of the questionnaire asked for the observed effects of specific psychotropic substances on sexual behaviour. The results support the evidence reported in the literature that neuroleptics and antidepressants are most likely to provoke sexual impairment. The results of the study are discussed in relation to the theoretical relevance of sexual side effects for the patient and the treatment and to the possibilities of a psychiatrist to prepare and inform his patient.
正如对有关精神科患者精神药物性副作用的文献综述所揭示的那样,性功能障碍(如勃起功能障碍或性高潮功能障碍)似乎是精神药物治疗的常见后果。在一项针对68名在诊所或医院工作的精神科医生的问卷调查研究中,评估了这些影响在精神科实践中的发生率和相关性。根据医生的回答,很少有患者自发报告药物的性副作用,尽管据推测这些副作用更为常见。不同类型的性功能损害被报告为药物的特定影响。由于医生认为这些影响通常会给患者的自尊以及治疗和依从性带来问题。基于精神科医生的经验,就性变化而言,患者在区分基础疾病和特定药物的影响方面处于令人惊讶的有利位置。问卷的一部分询问了特定精神药物对性行为的观察到的影响。结果支持了文献中报道的证据,即抗精神病药物和抗抑郁药物最有可能引发性功能损害。该研究的结果从性副作用对患者和治疗的理论相关性以及精神科医生为患者做好准备并提供信息的可能性方面进行了讨论。