Gadzhiev M G
Vestn Khir Im I I Grek. 1984 Feb;132(2):54-6.
Experimental (15 experiments in dogs) and clinical (56 patients) investigations have established two-phase changes in the system of hemostasis: hypocoagulation (first 2-3 days after trauma) changed by hypercoagulation (within 2-3 weeks after trauma). Antifibrinolytic and anticoagulative drugs are recommended for the prevention of hemorrhages and thromboses introduced under the control of hemostasis indices.
实验研究(对狗进行的15项实验)和临床研究(56例患者)已经证实止血系统存在两阶段变化:创伤后最初2 - 3天出现低凝状态,随后在创伤后2 - 3周转变为高凝状态。建议在止血指标监测下使用抗纤溶和抗凝药物来预防出血和血栓形成。