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[缺血性心脏病中的红细胞聚集与纤维蛋白原衍生物]

[Erythrocyte aggregation and fibrinogen derivatives in ischemic heart disease].

作者信息

Liusov V A, Parfenov A S, Belousov Iu B, Rudakov A V, Nechaeva V N

出版信息

Kardiologiia. 1978 Jun;18(6):42-8.

PMID:672018
Abstract

Aggregation of erythrocytes was determined in 50 patients with angina pectoris and myocardial infarction and in 20 subjects of the control group by rheoscopy after Schmid-Schoenbein. It is shown that in patients with ischemic heart disease aggregation of erythrocytes is considerably increased and the hydrodynamic strength of the aggregates is greater. The erythrocyte aggregation curve is some patients with ischemic heart disease was of a biexponential character in distinction to that in subjects of the control group, which was of the monoexponential type. It was found that the increase in the strength of the erythrocyte aggregation and in the rate of aggregate formation was due to fibrinogen and its complex compounds with decomposition products.

摘要

采用施密德 - 舍恩拜因流变学方法,对50例心绞痛和心肌梗死患者以及20名对照组受试者的红细胞聚集情况进行了测定。结果表明,缺血性心脏病患者的红细胞聚集显著增加,聚集体的流体动力学强度更大。与对照组受试者呈单指数型的红细胞聚集曲线不同,一些缺血性心脏病患者的红细胞聚集曲线具有双指数特征。研究发现,红细胞聚集强度和聚集体形成速率的增加是由于纤维蛋白原及其与分解产物的复合化合物所致。

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