Grigor'iants R A, Labova N M, Ignat'eva I F, Matveeva L S
Kardiologiia. 1978 Jun;18(6):73-6.
The clinical course of ischemic heart disease was followed-up for 3 to 5 years after coronarography in 91 patients with atherosclerotic affection of the coronary arteries who had not been given purposeful treatment. In 30.8 per cent in cases the clinical picture of the disease grew worse: angina of effort became more frequent angina at rest occurred (19.8%), and myocardial infarction (7.7%) and symptoms of circulatory insufficiency (3.3%) developed. A lethal outcome was recorded in 16.5% of cases. A connection between the extent of the atherosclerotic process (the number of vessels involved) and the advancement of the disease was revealed.
对91例未接受针对性治疗的冠状动脉粥样硬化性疾病患者进行了冠状动脉造影，并对其缺血性心脏病的临床病程进行了3至5年的随访。在30.8%的病例中，疾病的临床表现恶化：劳力性心绞痛发作更频繁，出现静息性心绞痛（19.8%）、心肌梗死（7.7%）和循环功能不全症状（3.3%）。16.5%的病例出现了致命结局。研究发现了动脉粥样硬化进程的程度（受累血管数量）与疾病进展之间的关联。
