Anttila S, Sutinen S, Pääkkö P, Finell B
Br J Dis Chest. 1984 Apr;78(2):195-200.
A 46-year-old woman suffering from rheumatoid arthritis developed numerous round opacities at the apex of the right lung 11 years after an exposure to dolomite . Resected lung showed discrete nodules, 0.8-2 cm in diameter, with central necrosis surrounded by palisading fibroblasts and a prominent inflammatory zone. A large number of birefringent dust particles were seen in the necrotic centres and around the nodules. By electron microscopy the particles were dense, mostly elongated and lamellar, varying from 0.005 to 3 microns in width, and from 0.1 to 6.5 microns in length. Energy dispersive x-ray microanalysis of the dust particles gave elemental spectra with high spikes of silicon, aluminium and potassium, and minimal magnesium, calcium, iron and titanium. According to chemical analysis, the original dolomite consisted almost entirely of magnesium and calcium carbonates and only of traces of silicon, aluminium and potassium. Apparently the human organism can better eliminate calcium and magnesium carbonates than silicon, aluminium and potassium.
一名46岁患类风湿性关节炎的女性，在接触白云石11年后，右肺尖出现大量圆形混浊影。切除的肺组织可见散在结节，直径0.8 - 2厘米，中央坏死，周围有成栅栏状排列的成纤维细胞及明显的炎症带。在坏死中心及结节周围可见大量双折射粉尘颗粒。电镜下，颗粒致密，大多呈细长形和层状，宽度0.005至3微米，长度0.1至6.5微米。粉尘颗粒的能量色散X射线微分析显示元素光谱中硅、铝和钾有高尖峰，而镁、钙、铁和钛含量极少。化学分析表明，原始白云石几乎完全由碳酸镁和碳酸钙组成，仅含微量的硅、铝和钾。显然，人体对碳酸钙和碳酸镁的清除能力比对硅、铝和钾的清除能力更强。
