Sotskiĭ O P, Akopov S E, Sarkisova G M, Chukhadzhian G A
Biull Eksp Biol Med. 1984 Apr;97(4):387-8.
During 4 months rats were given intraperitoneal injections of cerebrosides in a dose of 5 mg/kg bw. The measurements were taken of the arterial blood pressure and the function of blood cells. It has been demonstrated that as compared to the control, the experimental animals showed a significant elevation of the blood pressure, hyperaggregation of platelets and red cells, an increase in the ability of platelets to adhesion. It has been also disclosed that there was a decrease in the time of the occurrence of muscle fatigue and death under stress induced by forced dynamic work. The data obtained are of interest in the aspect of investigating the role played by glycolipids in the pathogenesis of cardiovascular diseases.
在4个月的时间里，给大鼠腹腔注射剂量为5毫克/千克体重的脑苷脂。测量动脉血压和血细胞功能。结果表明，与对照组相比，实验动物的血压显著升高，血小板和红细胞过度聚集，血小板黏附能力增强。还发现，在强迫动态工作诱导的应激下，肌肉疲劳和死亡出现的时间缩短。所获得的数据对于研究糖脂在心血管疾病发病机制中的作用具有重要意义。
