Metel'skiĭ S T
Biull Eksp Biol Med. 1984 May;97(5):563-5.
The author describes in detail the automatic continuous voltage clamp method for measuring the rate of active sodium transport across the rat small intestinal wall in vitro. The method allows the overcoming of two practical difficulties associated with the effects of edge damage and the existence of unstirrable layers, virtually reducing them to minimal. It is suggested that the effects of series resistance of subepithelial tissues should be taken into account by multiplying the measured value of the current by coefficient 1.31.