Stefanov A V, Kreĭnes V M, Dmitrieva A V, Lishko V K
Biull Eksp Biol Med. 1984 May;97(5):569-72.
The possibility of parenteral detoxification was studied in dogs with the experimental crush syndrome. Infusion of lecithin liposomes (25 and 50 mg/kg) prevented the development of postcompression toxemia and hemodynamic disorders characteristic for endogenous intoxication. The use of the nonspecific parenteral sorbent lecithin liposomes permitted the maintenance of an adequate function of the animals' cardiovascular system for 5 hours after decompression.
在患有实验性挤压综合征的犬类中研究了胃肠外解毒的可能性。输注卵磷脂脂质体(25和50毫克/千克)可预防内源性中毒特有的压缩后毒血症和血流动力学紊乱的发生。使用非特异性胃肠外吸附剂卵磷脂脂质体可使动物心血管系统在减压后5小时内维持适当功能。