Orr J P
Can J Comp Med. 1984 Apr;48(2):219-22.
A highly malignant fibrosarcoma which arose in or close to the mammary gland of a 12 year old Ayrshire cow, with metastases in local lymph nodes, lungs, liver, kidney and adrenal glands has been described. The tumors were densely cellular and consisted of interweaving bands of fusiform cells with a high mitotic index. Infiltration of normal tissues and invasion of blood vessels were characteristic features. Ultrastructural study of the cells revealed mesenchymal cells with abundance of rough endoplasmic reticulum and cytoplasmic vesicles and they were closely invested with collagen fibers.
一头12岁的艾尔夏奶牛乳腺内或乳腺附近出现了一种高度恶性的纤维肉瘤，并伴有局部淋巴结、肺、肝、肾和肾上腺转移，此病例已被报道。肿瘤细胞密集，由具有高有丝分裂指数的梭形细胞交织带组成。浸润正常组织和侵犯血管是其特征性表现。对细胞的超微结构研究显示，间充质细胞含有丰富的粗面内质网和胞质小泡，且紧密包裹着胶原纤维。
