Ochsenfahrt H
Fortschr Med. 1984 Apr 5;102(13):355-60.
Adverse drug reactions reflect neither malice on the part of the drug manufacturer, nor negligence on the part of the physician, but are simply the unavoidable price we have to pay to secure the largely positive effects of drug treatment. Our objective can only be to achieve the highest level of safety while keeping the risk as small as possible in comparison with the benefit obtained. Drug evaluation requires a knowledge both of the efficacy and any attendant possible risks of a given drug. With this in mind, since 1961, the Committee on the Safety of Medicines has been collecting and assessing reports on adverse drug reactions. The experience thus gained serves as a basis for the views of the medical profession on problems of drug safety, as also for the individual counselling of the practising physician. "Physicians counsel physicians on the prescribing of drugs" thus does not mean that some of us are wiser than others, but that we are engaged in a mutually beneficial exchange of individual experience.
药物不良反应既不反映制药商的恶意，也不反映医生的疏忽，而仅仅是我们为确保药物治疗的主要积极效果而不得不付出的不可避免的代价。我们的目标只能是在与所获得的益处相比将风险保持在尽可能小的同时，实现最高水平的安全性。药物评估需要了解特定药物的疗效和任何伴随的可能风险。出于这一考虑，自1961年以来，药品安全委员会一直在收集和评估药物不良反应报告。由此获得的经验既作为医学界对药物安全问题看法的基础，也作为对执业医生进行个别咨询的依据。“医生就药物处方相互提供咨询”因此并不意味着我们中的一些人比其他人更明智，而是意味着我们参与了个体经验的互利交流。
