Swerlick R A, Cooper P H
J Am Acad Dermatol. 1984 Mar;10(3):466-72. doi: 10.1016/s0190-9622(84)80096-1.
Cheilitis glandularis (CG) has been attributed to hyperplasia of labial salivary glands. We studied labial biopsy specimens of five patients with clinical CG and compared their salivary tissue with that seen in patients without CG. The labial glands from patients with CG did not differ in size, depth, or histologic appearance from those seen in the controls. They showed little or no inflammation and no hyperplasia. We also reviewed forty-eight cases of CG described in the literature. The accompanying photomicrographs nearly always depicted normal-appearing labial salivary glands. The case histories and clinical descriptions suggested that many examples of CG were manifestations of actinic cheilitis, whereas others may have been unusual presentations of atopic or factitious cheilitis. We believe CG represents an unusual reaction pattern in response to chronic irritation of the lips and is unrelated to labial salivary gland hyperplasia.
腺性唇炎（CG）被认为是唇唾液腺增生所致。我们研究了5例临床诊断为腺性唇炎患者的唇部活检标本，并将其唾液组织与无腺性唇炎患者的唾液组织进行了比较。腺性唇炎患者的唇腺在大小、深度或组织学外观上与对照组并无差异。它们几乎没有炎症或根本没有炎症，也没有增生。我们还回顾了文献中描述的48例腺性唇炎病例。所附的显微照片几乎总是显示唇唾液腺外观正常。病例记录和临床描述表明，许多腺性唇炎病例是光化性唇炎的表现，而其他病例可能是特应性或人为性唇炎的不寻常表现。我们认为腺性唇炎是对唇部慢性刺激的一种不寻常反应模式，与唇唾液腺增生无关。
