Kendall M E, Fields J P, King L E
J Am Acad Dermatol. 1984 May;10(5 Pt 2):903-5. doi: 10.1016/s0190-9622(84)80443-0.
A patient with cutaneous mastocytosis had intractable pruritus but no visible skin lesions. Skin biopsies and urinary histamine and prostaglandin D2 metabolite assays confirmed the diagnosis. Adding therapy with psoralens and ultraviolet A to the antihistamine regimen markedly decreased the patient's pruritus. In patients with pruritus, flushing, syncope, or other symptoms associated with mastocytosis, this diagnosis should be considered even in the absence of specific skin lesions.
一名皮肤肥大细胞增多症患者有顽固性瘙痒，但无可见皮肤病变。皮肤活检以及尿液组胺和前列腺素D2代谢产物检测确诊了该疾病。在抗组胺治疗方案中加用补骨脂素和紫外线A疗法显著减轻了患者的瘙痒。对于有瘙痒、潮红、晕厥或其他与肥大细胞增多症相关症状的患者，即使没有特定的皮肤病变也应考虑这一诊断。
