Bergh T, Nillius S J, Enoksson P, Wide L
J Endocrinol Invest. 1984 Apr;7(2):133-6. doi: 10.1007/BF03348403.
A 21-year-old amenorrheic woman with hyperprolactinemia had rapid pituitary tumor enlargment during a bromocriptine-induced pregnancy. Before treatment the sella turcica was normal. In the 31st week of pregnancy she developed bitemporal hemianopsia and markedly decreased visual acuity. Computerized tomography showed a pituitary adenoma with suprasellar extension. Reinstitution of bromocriptine therapy resulted in rapid recovery of normal vision and radiologically verified tumor regression. Pregnancy continued to term and a healthy child was born. If pituitary tumor complications should occur during pregnancy, reinstitution of bromocriptine is the primary treatment of choice.
一名21岁的闭经女性,患有高泌乳素血症,在溴隐亭诱发的妊娠期间垂体肿瘤迅速增大。治疗前蝶鞍正常。妊娠31周时,她出现双颞侧偏盲,视力明显下降。计算机断层扫描显示垂体腺瘤并向鞍上扩展。重新使用溴隐亭治疗后,视力迅速恢复正常,影像学证实肿瘤缩小。妊娠持续至足月,产下一名健康婴儿。如果妊娠期间发生垂体肿瘤并发症,重新使用溴隐亭是主要的治疗选择。