细胞外钠去除对色氨酸摄入大鼠皮层切片和突触体的相反作用。
Opposite effects of extracellular sodium removal on the uptake of tryptophan into rat cortical slices and synaptosomes.
作者信息
Wilkinson L S, Collard K J
出版信息
J Neurochem. 1984 Jul;43(1):274-5. doi: 10.1111/j.1471-4159.1984.tb06708.x.
Abstract
The removal of extracellular sodium decreased L-tryptophan (L-TRP) uptake into brain slices but increased uptake into synaptosomes. The uptake of 5-hydroxytryptamine (5-HT) was inhibited in both preparations under these conditions. It is suggested that the different effects on L-TRP uptake may be due to differences in cellular composition between the two preparations rather than to any differences in sample handling.
摘要
去除细胞外钠会减少脑片对L-色氨酸（L-TRP）的摄取，但会增加对突触体的摄取。在这些条件下，两种制剂中5-羟色胺（5-HT）的摄取均受到抑制。有人认为，对L-TRP摄取的不同影响可能是由于两种制剂细胞组成的差异，而非样品处理上的任何差异。
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