Stangel J J, Nisbet J D, Settles H
J Reprod Med. 1984 Mar;29(3):143-56.
Postoperative abdominal adhesion formation can undo the reconstructive work of the infertility surgeon. Adhesions can form in as little as three hours after surgery. Most adhesions are transient and lyse spontaneously within 72 hours of surgery. Such factors as tissue trauma, anoxia and ischemia cause a reduction in plasminogen activator activity that is strongly correlated with the persistence and progression of postoperative adhesions. Adhesions can be prevented by a proper and meticulous surgical technique emphasizing preservation of tissue without abrasion, anoxia or ischemia. Dextran, antiprostaglandins, antibiotics, steroids, antihistamines, anticoagulants and enzymes have various roles. Our current regimen involves Hyskon, Motrin and deoxycycline.
术后腹部粘连的形成会破坏不孕不育外科医生的重建工作。粘连可在术后短短三小时内形成。大多数粘连是暂时的，会在术后72小时内自行溶解。组织创伤、缺氧和缺血等因素会导致纤溶酶原激活物活性降低，这与术后粘连的持续和进展密切相关。通过强调在不造成擦伤、缺氧或缺血的情况下保存组织的恰当且细致的手术技术，可以预防粘连。右旋糖酐、抗前列腺素、抗生素、类固醇、抗组胺药、抗凝剂和酶都有不同作用。我们目前的治疗方案包括使用Hyskon、布洛芬和脱氧土霉素。
