Wagner V M, Baehner R L
Med Pediatr Oncol. 1984;12(3):166-8. doi: 10.1002/mpo.2950120304.
Two children with ANLL in complete remission developed testicular relapse 18 and 34 months after diagnosis. Their clinical presentation was similar to that observed in patients with ALL. Although the testicular leukemia responded to between 2,400 and 3,000 rads, bone marrow relapse occurred within 4 months and death within 6 months of the testicular relapse. This points out the need for surveillance of the testicles in males with ANLL, and raises the question of need for testicular biopsy among long-time male survivors.
两名急性非淋巴细胞白血病(ANLL)完全缓解的儿童在诊断后18个月和34个月出现睾丸复发。他们的临床表现与急性淋巴细胞白血病(ALL)患者相似。尽管睾丸白血病对2400至3000拉德的放疗有反应,但在睾丸复发后4个月内发生骨髓复发,6个月内死亡。这指出了对ANLL男性患者进行睾丸监测的必要性,并提出了长期男性幸存者是否需要进行睾丸活检的问题。