用精神药物长期治疗后大鼠脑中氟化物刺激的腺苷酸环化酶活性。
Fluoride-stimulated adenylate cyclase activity in rat brain following chronic treatment with psychotropic drugs.
作者信息
Andersen P H, Klysner R, Geisler A
出版信息
Neuropharmacology. 1984 Apr;23(4):445-7. doi: 10.1016/0028-3908(84)90253-3.
PMID:6728130
Abstract
Chronic treatment with imipramine and reserpine increased fluoride-stimulated activity of adenylate cyclase in homogenates of cerebral cortex and "limbic" forebrain of the rat. Concomitant treatment with lithium counteracted this effect, while lithium alone had no effect on the activity of adenylate cyclase.
摘要
用丙咪嗪和利血平进行长期治疗可增加大鼠大脑皮层和“边缘”前脑匀浆中氟化物刺激的腺苷酸环化酶活性。锂盐联合治疗可抵消这种作用，而单独使用锂盐对腺苷酸环化酶活性没有影响。
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