Kossut M, Hand P
Neurosci Lett. 1984 Apr 20;46(1):1-6. doi: 10.1016/0304-3940(84)90189-7.
A column of SI cortex responding to stimulation of a single vibrissa can be visualized with [14C]2-deoxyglucose (2-DG) autoradiography. The development of C3 vibrissal column was investigated in rat pups aged 2, 4, 6, 8, 12 and 21 days. A patch of label corresponding to higher glucose utilization appeared at postnatal day (p.d.) 4 to 6 in the cortical plate. Between p.d. 6 and 12 it developed into a spindle-shaped column. The infragranular layers showed metabolic activation later than the upper laminae. The suitability of the 2-DG technique for studies of infant mammalian brain is discussed.
通过[14C]2-脱氧葡萄糖（2-DG）放射自显影术可以观察到体感皮层中对单一触须刺激产生反应的一列神经元。对2、4、6、8、12和21日龄的幼鼠C3触须柱的发育情况进行了研究。在出生后第（p.d.）4至6天，皮质板中出现了一块对应较高葡萄糖利用率的标记区域。在p.d. 6至12天之间，它发育成纺锤形柱。颗粒下层的代谢激活比上层出现得晚。讨论了2-DG技术在研究幼年哺乳动物大脑方面的适用性。
