混合胶束：相比之下，是ω-123I-十七烷酸的一种新的无问题解决方案。
Mixed micells: a new problem-free solution for omega-123I-heptadecanoic acid in comparison.
作者信息
Schubiger P A, Argentini M, Bläuenstein P, Lerch R
出版信息
Nuklearmedizin. 1984 Feb;23(1):27-8.
The most commonly used reagents for solubilization of 123I fatty acids have very serious drawbacks. Human serum albumin solubilizes the fatty acid only slowly and TWEEN 80 is not free of stability problems. Furthermore adverse reactions in human applications cannot be excluded. In comparison, the newly introduced mixed micells look very favourable: fast solubilization, good stability and no adverse reactions. Biodistribution experiments on rats show an adequate performance of the micells . Hitherto this solution has been applied in more than 200 patients without any complication.
用于溶解123I脂肪酸的最常用试剂存在非常严重的缺陷。人血清白蛋白只能缓慢地溶解脂肪酸，吐温80也存在稳定性问题。此外，不能排除在人体应用中的不良反应。相比之下，新引入的混合微团看起来非常有利：溶解速度快、稳定性好且无不良反应。对大鼠的生物分布实验表明微团性能良好。迄今为止，这种溶液已应用于200多名患者，没有出现任何并发症。
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