Antibiotics for intraabdominal sepsis. Selection of an effective combination.

Optimum management of intraabdominal sepsis requires the judicious use of appropriate surgical procedures and simultaneous antibiotic administration. A number of appropriate antibiotics and antibiotic combinations are available for intraabdominal sepsis, but most data still favor combinations of an antiaerobic drug, most often an aminoglycoside, and an antianaerobic drug--and possibly a third agent effective against enterococci.