Mahony B S, Filly R A, Callen P W, Hricak H, Golbus M S, Harrison M R
Radiology. 1984 Jul;152(1):143-6. doi: 10.1148/radiology.152.1.6729104.
In an attempt to predict histologic fetal renal dysplasia among fetuses with obstructive uropathy, three antenatal sonographic features (presence of renal cortical cysts, echogenicity of renal parenchyma, and degree of hydronephrosis) were studied. Identification of renal cortical cysts in the kidneys of fetuses with obstructive uropathy enabled accurate prediction of renal dysplasia. Of 49 fetal kidneys with obstructive uropathy, all 15 kidneys with sonographically visible cortical cysts had severe but not necessarily lethal dysplasia (accuracy of positive prediction = 100%). Of 15 obstructed but nondysplastic fetal kidneys, none had sonographically visible cysts (specificity = 100%). The absence of fetal renal cysts on antenatal sonography, however, did not exclude the presence of dysplasia. Assessment of the echogenicity of renal parenchyma and the degree of hydronephrosis are of only limited value in predicting whether an obstructed fetal kidney will show histologic dysplasia.
为了预测患有尿路梗阻的胎儿的组织学胎儿肾发育不良，研究了三种产前超声特征（肾皮质囊肿的存在、肾实质的回声性和肾积水程度）。在患有尿路梗阻的胎儿肾脏中识别肾皮质囊肿能够准确预测肾发育不良。在49个患有尿路梗阻的胎儿肾脏中，所有15个超声可见皮质囊肿的肾脏都有严重但不一定致命的发育不良（阳性预测准确率=100%）。在15个梗阻但无发育不良的胎儿肾脏中，没有一个有超声可见囊肿（特异性=100%）。然而，产前超声检查未发现胎儿肾囊肿并不排除发育不良的存在。评估肾实质的回声性和肾积水程度在预测梗阻性胎儿肾脏是否会出现组织学发育不良方面价值有限。
