de Rohan Chabot P, Gueguen B, Patte D, Gajdos P, Raphael J C, Goulon M
Rev Neurol (Paris). 1984;140(3):207-11.
A typical case of glycyrrhizin-induced hypokalemic paralysis in a diabetic patient is presented. Hypokalemia was responsible for a generalized muscle weakness with a rise in serum muscular enzymes and cardiovascular disorders, which improved under potassium supplementation and spironolactone therapy. The pseudoaldosteronism syndrome with low plasma renin activity and aldosteron suggested aldosteron -like liquorice intoxication. Patient's interrogation revealed regular consumption of a common aperitive drink: a non-alcoholic pastis containing small amounts of glycyrrhizin. The discrepancy between the severity of clinical manifestations and the ingested amounts of glycyrrhizin is explained by the diabetic state.
本文介绍了一例糖尿病患者因甘草酸导致低钾性麻痹的典型病例。低钾血症导致全身肌无力，血清肌肉酶升高及心血管紊乱，补充钾及螺内酯治疗后症状改善。血浆肾素活性和醛固酮降低的假性醛固酮增多症综合征提示类似醛固酮的甘草中毒。询问患者得知其经常饮用一种常见的开胃饮料：一种含少量甘草酸的非酒精性法国茴香酒。糖尿病状态解释了临床表现严重程度与摄入甘草酸量之间的差异。
