Carvalho F M, Barreto M L, Silvany-Neto A M, Waldron H A, Tavares T M
Sci Total Environ. 1984 Apr 5;35(1):71-84. doi: 10.1016/0048-9697(84)90369-3.
A prevalence study of anaemia was carried out amongst children, aged one to nine years, living near a lead smelter in Santo Amaro City, Northeast Brazil. It was found that the variation in haemoglobin levels was significantly associated with malnutrition and with the interaction between malnutrition and iron deficiency, but not with lead poisoning, iron deficiency, or hookworm infection, having allowed for the effects of age, area of residence, family per capita income and race. The effect of the interaction between malnutrition and iron deficiency on haemoglobin levels was most prominent amongst children aged one year and amongst those living in the most deprived area. The lack of demonstrable interaction between lead poisoning and iron deficiency in the causation of anaemia amongst these children is discussed.
在巴西东北部圣阿马罗市一家铅冶炼厂附近居住的1至9岁儿童中开展了一项贫血患病率研究。研究发现,在考虑了年龄、居住地区、家庭人均收入和种族的影响后,血红蛋白水平的变化与营养不良以及营养不良和缺铁之间的相互作用显著相关,但与铅中毒、缺铁或钩虫感染无关。营养不良和缺铁之间的相互作用对血红蛋白水平的影响在1岁儿童以及生活在最贫困地区的儿童中最为显著。文中讨论了在这些儿童贫血病因中铅中毒与缺铁之间缺乏明显相互作用的情况。