Robertson L J, Crompton D W, Sanjur D, Nesheim M C
Department of Zoology, University of Glasgow, Scotland.
Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):654-6. doi: 10.1016/0035-9203(92)90176-d.
The blood haemoglobin concentrations and intestinal helminth infections were surveyed in 658 children aged between 6 and 12 years attending 4 primary schools in Coclé Province, Panama, in November 1987. 147 (22.3%) of the children were judged to have haemoglobin concentrations indicative of iron-deficiency anaemia. Blood haemoglobin concentrations were significantly lower in children with heavier Trichuris trichiura infections (> 5000 eggs/g) (P = 0.014), and in children with dual infections of both hookworm and T. trichiura (P = 0.005). Children with concomitant T. trichiura and hookworm infections were also significantly more likely to have blood haemoglobin levels indicative of anaemia than children who were uninfected or had single infections with either of these helminths (P < 0.005). In a longitudinal study involving 171 children selected from the original 658, blood haemoglobin concentrations were measured again in November 1988. Children who were considered to show an improvement in both hookworm and T. trichiura infections over this 12 month period showed a significantly greater increase in blood haemoglobin concentrations than children who had remained uninfected with either of these helminths throughout the study period (P < 0.05).
1987年11月，对巴拿马科克莱省4所小学的658名6至12岁儿童进行了血血红蛋白浓度和肠道蠕虫感染情况调查。147名（22.3%）儿童被判定血血红蛋白浓度表明患有缺铁性贫血。感染较重的毛首鞭形线虫（>5000个虫卵/克）的儿童血血红蛋白浓度显著较低（P = 0.014），同时感染钩虫和毛首鞭形线虫的儿童血血红蛋白浓度也显著较低（P = 0.005）。与未感染或仅单一感染这两种蠕虫之一的儿童相比，同时感染毛首鞭形线虫和钩虫的儿童血血红蛋白水平表明患有贫血的可能性也显著更高（P < 0.005）。在一项对从最初的658名儿童中选出的171名儿童进行的纵向研究中，1988年11月再次测量了血血红蛋白浓度。在这12个月期间被认为钩虫和毛首鞭形线虫感染情况均有改善的儿童，其血血红蛋白浓度的增加幅度显著大于在整个研究期间未感染这两种蠕虫之一的儿童（P < 0.05）。
