Bradley E L, Nasrallah S M
Surgery. 1984 Jun;95(6):640-3.
This study was undertaken to determine whether fat absorption is improved following longitudinal pancreaticojejunostomy. Ten consecutive patients with chronic pancreatitis underwent measurement of fat absorption (fecal fat, 14C-labeled phenylacetic dipalmitate oil absorption test) before and after operation. Fecal fat increased in 8 of 10 patients following side-to-side pancreaticojejunostomy. However, the average postoperative fecal fat increase of 4.3 gm was of no clinical significance. The observed mild postoperative decline in fat absorption was confirmed by the 14C-labeled phenylacetic dipalmitate test. An improvement in postoperative fat absorption following side-to-side pancreaticojejunostomy Roux-en-Y should not be expected. The primary indication for this procedure for patients with chronic pancreatitis continues to be intractable pain.
本研究旨在确定纵向胰空肠吻合术后脂肪吸收是否得到改善。连续10例慢性胰腺炎患者在手术前后接受了脂肪吸收测量（粪便脂肪、14C标记的苯乙酸二棕榈酸酯油吸收试验）。在侧侧胰空肠吻合术后，10例患者中有8例粪便脂肪增加。然而，术后粪便脂肪平均增加4.3克并无临床意义。14C标记的苯乙酸二棕榈酸酯试验证实了术后脂肪吸收出现轻度下降。不应期望侧侧胰空肠吻合Roux-en-Y术后脂肪吸收会有所改善。对于慢性胰腺炎患者，该手术的主要适应证仍然是顽固性疼痛。
