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一种大型镁合金瘤胃丸预防奶牛低镁血症性搐搦的效果

Efficacy of a large magnesium alloy rumen bolus in the prevention of hypomagnesemic tetany in cows.

作者信息

Stuedemann J A, Wilkinson S R, Lowrey R S

出版信息

Am J Vet Res. 1984 Apr;45(4):698-702.

PMID:6731982
Abstract

Two cow-calf grazing studies and 2 rate-of-disappearance trials in steers surgically prepared with rumen fistula were conducted to evaluate the efficacy of a large Mg alloy rumen bolus in preventing hypomagnesemic tetany (grass tetany). The mineral composition of the forage and results of study of 2 cows in the cow-calf studies indicated that an environment conducive to the occurrence of grass tetany existed. Grass tetany occurred in a cow that was given a Mg bolus and in a control cow. Administration of 1 or 2 mg boluses did not affect blood serum Mg, Ca, P, and K concentrations. Bolus treatment did not affect cow-calf performance or conception rate. The rate of weight loss of the boluses in the surgically prepared steers (rumen fistula) ranged from 0.71 to 1.43 g/day or 0.66 to 1.33 g of Mg/day. Steer differences affected the rates of disappearance patterns of the boluses. The rate of disappearance was relatively constant over a 175-day period and regurgitation or passage was not a problem. Although administration of the boluses could have prevented tetany in some animals (borderline), the rate of Mg release appears too slow to be highly effective in preventing grass tetany.

摘要

进行了两项犊牛放牧研究以及两项在安装了瘤胃瘘管的阉牛身上开展的消失速率试验,以评估一种大型镁合金瘤胃丸剂预防低镁血症搐搦(青草搐搦)的效果。犊牛研究中草料的矿物质组成以及两头母牛的研究结果表明存在有利于青草搐搦发生的环境。在一头服用镁丸剂的母牛和一头对照母牛身上都发生了青草搐搦。服用1或2毫克的丸剂不影响血清镁、钙、磷和钾的浓度。丸剂处理不影响犊牛的生产性能或受孕率。在安装了瘤胃瘘管的阉牛身上,丸剂的失重速率为每天0.71至1.43克,即每天损失0.66至1.33克镁。阉牛个体差异影响丸剂的消失模式速率。在175天的时间段内,消失速率相对恒定,反流或排出不是问题。尽管在某些动物(临界状态)中服用丸剂本可预防搐搦,但镁的释放速率似乎过慢,难以在预防青草搐搦方面高度有效。

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