Franco D P, Kinasewitz G T, Markham R V, Tucker W Y, George R B
Am Rev Respir Dis. 1984 Jun;129(6):1021-2. doi: 10.1164/arrd.1984.129.6.1021.
A patient with platypnea and orthodeoxia after right pneumonectomy is described. Cardiac catheterization revealed arterial desaturation in the upright position associated with increased right to left intracardiac shunting through a patent foraman ovale. The absence of a pressure gradient between the left and right atrium in either the supine or sitting position indicated that the orthodeoxia resulted from an increase in streaming of blood from the inferior vena cava to the left atrium caused by mechanical distortion of the interatrial septum.
本文描述了一位右肺切除术后出现平卧呼吸困难和直立性低氧血症的患者。心导管检查显示，直立位时动脉血氧饱和度降低，同时通过未闭卵圆孔的右向左心内分流增加。仰卧位或坐位时左心房和右心房之间均不存在压力梯度，这表明直立性低氧血症是由房间隔机械性扭曲导致下腔静脉血液向左心房的血流增加所致。
