Koch B, Galioto F M, Kelleher J, Goldstein D
Arch Phys Med Rehabil. 1984 Jun;65(6):324-6.
Eleven boys, 8.3 to 15.5 (mean 11.6) years old, with hemophilia, were studied by bicycle ergometry to determine their physical fitness. Parameters analyzed and compared to data for normal children included total work, mean power minutes of exercise, heart rate (HR), and blood pressure (BP), as well as catecholamine levels. The hemophilic child performs significantly less total work (67%), mean power (49%), minutes of exercise, (30%), and HR (8%). There were no differences in BP. Norepinephrine rose from a resting level of 204.5 to 652pg /ml after exercise, and epinephrine rose from 20.5 to 76.6pg/ml, levels comparable to those achieved by normal children during exercise. Children with hemophilia demonstrate poor exercise performance, which we believe is due to a lack of physical conditioning. Recommendations are made for individual exercise prescriptions to improve the fitness of these children.
对11名年龄在8.3至15.5岁（平均11.6岁）的血友病男孩进行了自行车测力计测试，以确定他们的身体素质。分析了各项参数，并与正常儿童的数据进行比较，包括总功、平均功率运动分钟数、心率（HR）、血压（BP）以及儿茶酚胺水平。血友病患儿的总功（67%）、平均功率（49%）、运动分钟数（30%）和心率（8%）明显较低。血压没有差异。运动后，去甲肾上腺素从静息水平的204.5 pg/ml升至652 pg/ml，肾上腺素从20.5 pg/ml升至76.6 pg/ml，这些水平与正常儿童运动时达到的水平相当。血友病患儿的运动表现较差，我们认为这是由于缺乏体能训练所致。针对改善这些儿童的健康状况，提出了个性化运动处方的建议。
