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关于愈创木酚甘油醚作为马匹全身麻醉辅助药物使用的观察报告。

Observations on the use of glyceryl guaiacolate as an adjunct to general anaesthesia in horses.

作者信息

Kalhoro A B, Rex M A

出版信息

Aust Vet J. 1984 Feb;61(2):49-53. doi: 10.1111/j.1751-0813.1984.tb07191.x.

DOI:10.1111/j.1751-0813.1984.tb07191.x
PMID:6732668
Abstract

Twenty-one horses undergoing clinical surgery and diagnostic procedures received 15% glyceryl guaiacolate followed by a rapid intravenous injection of a thiobarbiturate for induction of anaesthesia. Premedication was with atropine and acepromazine. Induction was smooth and free from problems apart from transient apnoea in some horses. Maintenance of anaesthesia was with oxygen and halothane administered by means of a closed circle system with soda-lime absorber and with the vaporiser out of circuit. During the period immediately following induction, the heart rate increased and the respiratory rate fell. Blood gas estimations were carried out on 6 horses during anaesthesia. These horses showed respiratory acidosis. Arterial blood oxygen tension values were above those reported in conscious horses. Use of glyceryl guaiacolate in this way provides a safe induction and enables transition to a stable maintenance period which is followed by a quiet and uneventful recovery.

摘要

21匹接受临床手术和诊断程序的马接受了15%的愈创木酚甘油醚,随后快速静脉注射硫代巴比妥酸盐以诱导麻醉。术前用药为阿托品和乙酰丙嗪。除了一些马出现短暂呼吸暂停外,诱导过程顺利且无问题。麻醉维持采用氧气和氟烷,通过带有钠石灰吸收器的闭合回路系统给药,蒸发器不在回路中。在诱导后的 immediately 期间,心率增加,呼吸频率下降。麻醉期间对6匹马进行了血气测定。这些马表现出呼吸性酸中毒。动脉血氧张力值高于清醒马的报告值。以这种方式使用愈创木酚甘油醚可提供安全的诱导,并能顺利过渡到稳定的维持期,随后是安静且平稳的恢复。 (注:原文中“immediately following induction”中“immediately”翻译为“紧接着”更通顺些,“在紧接着诱导后的期间”;“apart from transient apnoea in some horses”翻译为“除了一些马匹出现短暂呼吸暂停外”表述更准确)

调整后的译文

21匹接受临床手术和诊断程序的马接受了15%的愈创木酚甘油醚,随后快速静脉注射硫代巴比妥酸盐以诱导麻醉。术前用药为阿托品和乙酰丙嗪。除了一些马匹出现短暂呼吸暂停外,诱导过程顺利且无问题。麻醉维持采用氧气和氟烷,通过带有钠石灰吸收器的闭合回路系统给药,蒸发器不在回路中。在诱导后紧接着的期间,心率增加,呼吸频率下降。麻醉期间对6匹马进行了血气测定。这些马表现出呼吸性酸中毒。动脉血氧张力值高于清醒马的报告值。以这种方式使用愈创木酚甘油醚可提供安全的诱导,并能顺利过渡到稳定的维持期,随后是安静且平稳的恢复。

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