Holler E
Biochem Biophys Res Commun. 1984 May 16;120(3):1037-43. doi: 10.1016/s0006-291x(84)80211-9.
Diadenosine 5',5'''-P1,P4-tetraphosphate was shown by circular dichroic measurements to bind to metal ions (Mg2+, Ca2+, Mn2+, Co2+, Zn2+), to biogenic amines (cadaverine, putrescine, spermidine, spermine), to L-arginine, to proteins (lysozyme, bovine serum albumin, Arg-rich histone f3, Lys-rich histone), and to poly(dT). Most cations effect destacking of the intramolecular adenine rings. Poly(dT) bound to the dinucleotide with a stoichiometry of 2 residues TMP per molecule of adenosine 5',5'''-P1,P4-tetraphosphate.
通过圆二色性测量表明，5',5'''-P1,P4-四磷酸二腺苷可与金属离子（Mg2+、Ca2+、Mn2+、Co2+、Zn2+）、生物胺（尸胺、腐胺、亚精胺、精胺）、L-精氨酸、蛋白质（溶菌酶、牛血清白蛋白、富含精氨酸的组蛋白f3、富含赖氨酸的组蛋白）以及聚（dT）结合。大多数阳离子会导致分子内腺嘌呤环的解堆叠。聚（dT）与二核苷酸结合，化学计量比为每分子5',5'''-P1,P4-四磷酸腺苷有2个TMP残基。
