Innocenti G M, Clarke S
Brain Res. 1984 May;316(1):143-8. doi: 10.1016/0165-3806(84)90019-1.
A transitory projection from primary and secondary auditory areas to the contralateral and ipsilateral areas 17 and 18 exists in newborn kittens. Distinct neuronal populations project to ipsilateral areas 17-18, contralateral areas 17-18 and contralateral auditory cortex; they are at different depth in layers II, III, and IV. By postnatal day 38 the auditory to visual projections have been lost, apparently by elimination of axons rather than by neuronal death. While it was previously reported that the elimination of transitory axons is responsible for focusing the origin of callosal connections to restricted portions of sensory areas it now appears that similar events play a more general role in the organization of cortico-cortical networks. Indeed, the elimination of juvenile projections is largely responsible for determining which areas will be connected in the adult.
新生小猫中存在从初级和次级听觉区域到对侧和同侧17区和18区的短暂投射。不同的神经元群体投射到同侧17 - 18区、对侧17 - 18区和对侧听觉皮层；它们在第II、III和IV层处于不同深度。到出生后第38天，听觉到视觉的投射已经消失，显然是通过轴突的消除而不是神经元死亡。虽然之前有报道称，短暂轴突的消除负责将胼胝体连接的起源集中到感觉区域的受限部分，但现在看来，类似的事件在皮质 - 皮质网络的组织中发挥着更普遍的作用。事实上，幼年投射的消除在很大程度上决定了成体中哪些区域会相互连接。
