Griffiths R W, Briggs J C, Hiles R W
Bristol Med Chir J. 1984 Apr;99(370):55-60.
In a retrospective review of 614 primary Stage I cutaneous malignant melanomata and 40 nonmelanoma lesions, the diagnostic accuracy(DA) for malignant melanoma was 86.2%. A positive preoperative clinical diagnosis of malignant melanoma was confirmed histologically in 564/604 (93.3%) of lesions. For 614 histologically proven malignant melanomata a correct pre-operative clinical diagnosis had been made in 564/614 (91.9%). An additional 172 patients were referred for wider excisional surgery within 3 months of a biopsy elsewhere. For the total 786 (614+172) patients, the incidence of biopsy of a clinicially unsuspected (but subsequently histologically proven) malignant melanoma prior to referral to the Plastic Surgery Unit was lowest for lesions of the head and neck (18.3%) and lower limb (19.0%), and highest (almost half of the patients) for lesions of the hands and fingers. Previous reports of the poor level of clinical diagnostic accuracy in cutaneous malignant melanoma have not been confirmed in the present study.
在一项对614例原发性I期皮肤恶性黑色素瘤和40例非黑色素瘤病变的回顾性研究中，恶性黑色素瘤的诊断准确率（DA）为86.2%。术前临床诊断为恶性黑色素瘤的病变中，564/604（93.3%）经组织学证实。对于614例经组织学证实的恶性黑色素瘤，术前临床诊断正确的有564/614（91.9%）。另外172例患者在其他地方活检后3个月内被转诊进行更广泛的切除手术。对于总共786例（614 + 172）患者，在转诊至整形外科之前，临床未怀疑（但随后经组织学证实）的恶性黑色素瘤活检发生率在头颈部病变（18.3%）和下肢病变（19.0%）中最低，而在手部和手指病变中最高（几乎占患者的一半）。目前的研究未证实先前关于皮肤恶性黑色素瘤临床诊断准确率低的报道。
